Article Abstract

LXRs are finally being adequately targeted in atherosclerosis

Authors: Julio Buñay, Silvère Baron, Jean-Marc A. Lobaccaro


Atherosclerosis is the major cause of morbidity and mortality (1). Schematically, plaque is mainly made of fat, cholesterol and calcium, builds up in the arteries, and limits the oxygen-rich blood flow. Serious problems obviously occur when the arteries become narrow and/or become too closed, enough to impede blood flow.