Immunosuppressive role of extracellular vesicles: HLA-G, an important player
Extracellular vesicles (EVs) are bilayer membrane structures composed of proteins, lipids and nucleic acids (DNA and RNA). Their specific cargo is peculiar and derives from the cell of origin. They have been involved in many physiological and pathological processes. Regarding immune biology, EVs play an important role, as they may enhance or suppress the immune system (1).