Liposteroid therapy for juvenile and adult dermatomyositis: efficacy and side effects

Hiroyuki Wakiguchi


Juvenile dermatomyositis (JDM) is a multisystem disease of uncertain origin that is defined by chronic inflammation of striated muscle and the skin (1). Similarities and differences between JDM and adult dermatomyositis (ADM) have been reported (1). We know that persistent muscle impairment, despite immunosuppressive therapy, is a common symptom for both patients with JDM and ADM. However, there is less information regarding the pathophysiology of JDM compared with ADM.