Article Abstract

Can xerostomia be further reduced by sparing parotid stem cells?

Authors: Avraham Eisbruch


Reducing xerostomia by sparing the parotid glands (PGs) has been the main rationale for intensity modulated radiotherapy (IMRT) in patients with head and neck cancer (HNC). Sparing the PGs by IMRT has indeed improved xerostomia compared with conventional radiotherapy in randomized studies (1-3), and has achieved even further improvement over time (4).


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