Article Abstract

Osteoporosis and strontium-substituted hydroxyapatites

Authors: Nikolaos Kourkoumelis

Abstract

Biomedical implants able to stimulate sufficient osteointegration in the vicinity of the bone-material interface are essential for reducing the patient’s immobility time and for stabilizing the implant fixation in the long term. Hydroxyapatite (HA) is a biocompatible and osteoconductive material which exhibits high affinity for host bone tissues through mineral surface reactions. The mechanism of the formation and strengthening of the bone-HA interface was studied using high-resolution transmission electron microscope (HRTEM) and energy-dispersive X-ray (EDX) analysis (1) and it was suggested that the transition of crystalline to amorphous HA is the first critical step in the bone-implant bonding.

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