Resected small cell lung cancer—what do we do next?

Small cell lung cancer (SCLC) accounts for only 15% of lung cancers diagnosed in the United States; however it represents the 5th leading cause of cancer related mortality (1). Cytotoxic chemotherapy, with or without radiation therapy, is the primary modality for the treatment of SCLC as this particular histology is exquisitely chemosensitive with initial response rates around 65% (2).